ROUTINE AND SPECIALIZED HISTOLOGY SUPPORT

• Routine paraffin processing of rodent and non-rodent tissues
• OCT embedding and cryosectioning, for special and IHC staining
• Customized bone decalcification methods
• Wide selection of special stains
• Extensive experience in bone work
• Customized ocular trimming and sectioning
• Specific and complex brain tissue trimming and processing

QUALITY IS OUR NUMBER ONE PRIORITY

Quality is our number one priority and we devote the time and attention necessary to achieve consistent and reliable results.

1. We hire people with good attitudes and work ethics
2. We make a continual investment in our employees
3. We are committed to ongoing growth and enhancement of our lab services
4. Microscopic quality checks and oversight from board-certified pathologists
5. Experience with advanced lab techniques
6. Adherence to SOPs and best practices

Taking these steps for each project, along with the oversight of our board certified pathologists and attention of each of our staff members, has afforded HistoTox Labs the ability to continually deliver high-quality results.  You can rely upon us to provide the support needed to allow you to make accurate, timely assessments throughout your pre-clinical programs.

• Acid Fast Ziehl-Neelsen (Acid-fast Bacilli)
• Alcian Blue (Acid Mucosubstances and Acetic Mucins)
• Alizarin Red S (Calcium)
• Brown and Brenn Gram Stain (Gram Positive and Negative Bacteria)
• Brown-Hopps Gram Stain (Gram Positive and Negative Bacteria)
• Colloidal Iron (Hemosiderin)
• Congo Red (Amyloid Fibrils, Elastic Fibers, and Eosinophil Granules)
• Cresyl Echt Violet (Nissl Substance)
• Fite’s Method for AFB (Lepra and Other Acid-fast Bacilli, Nocardia Filaments)
• Fontana Masson Method (Argentaffin Granules and Melanin)
• Giemsa (Blood Cell Differentiation)
• Gömöri Methenamine Silver (Fungal Organisms)
• Gordon and Sweets’ Method (Reticulin Fibers)
• Jones’ Silver (Basement Membranes)
• Lillie’s Allochrome Procedure (Nuclei, Cytoplasm, Muscle Cells, Reticular Connective Tissue, and Glomerular Basement Membranes)
• Mowry’s Modification of the Colloidal Iron Stain (Acid Mucopolysaccharides and Sialomucins)
• Oil Red O (Fat Cells and Neutral Fat)
• Periodic Acid-Schiff (Glycogen and Basement Membranes)
• Periodic Acid-Schiff Light Green (Fungal Organisms)
• Picro Sirius Red (Collagen)
• Rhodanine Method (Copper)
• Russel-Movat Pentacrome (Elastic Fibers, Collagen, Mucins, Muscle, and Fibrinoid)
• Safranin-O (Cartilage, Mast Cells)
• Succinate Dehydrogenase (Fast vs. Slow Twitch Muscle Fibers)
• Thioflavine S (Amyloid Deposits)
• Trichrome (Connective Tissue and Cytoplasm)
• Verhoeff’s Elastic (Elastic Fibers)
• Von Kossa (Calcium Salts)

HistoTox Labs can accommodate other specific or modified stains and/or procedures not listed.